"You can tune your rig with or without the amp inline and functioning, your choice but if you have an idea of how much output you need from your radio this will not be necessary."
aye, there's the rub. better yet, you need to have an idea of how much output you need from the amplifier. in the high power position with unregulated bias the ideal would be @ or just under 180WPEP from 45W of carrier on AM and the same PEP for SSB operation. the transmitter should be adjusted with the rf power control in the maximum clockwise position to obtain these power levels so that the maximum drive values cannot be exceeded. AMC will have to be backed down to control PEP using 30 mv. (-18dbm) of microphone signal input with the mic gain wide open. that's the idiot-proof method.
(i was not implying that anyone in this thread was an idiot.)
since the SD1446's come in 6 different flavors, (beta-gain) J, K, L, M, N and O, attempting to determine just exactly what amount of carrier an pep are required by the transmitter to produce the numbers above is almost impossible without making adjustments with the amplifier inline and operating.
in addition, you don't want to make any of these adjustments into an antenna system unless you know with all certainty that the load represented by the antenna is as equal to Z=50, X=0 as possible if you want any accuracy at all from your power/watt meter.
the 10W AM/FM drive rating for the amplifier mentioned earlier is best and most accurately interpreted as 10WPEP (Modulated) AM, 10WCarrier FM. a review of the POut VS. PIn Graph for the SD1446 operating @ 30Mhz. makes this rather clear.