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There are also many videos on Youtube on how to program the UV 5R... I did mine manually until my cable came which only took 4 days in the mail. I didnt order it from Hong Kong, there are places here that have the cable and its not expensive. 


If you dont want to keep hitting  the MENU then a number on the pad , you can press MENU and use the up or down arrow to scroll to what you want such as OFFSET, or the CTCSS tones.  I used the  up /down arrows on the keypad   it's doable and a pain but not as bad as  manually doing a Yaesu.  


The software can be downloaded just Google search and you will see UV 5R software, and also the USB drivers for Windows Vista or 7 or XP whatever you're using.  Install the driver,  load the program  have the USB cable onto the HT, and turn it on, then select the comm port, you have a choice of 8 of them, its usually Comm 3,  or 4, then select  Program at the top of your software and pick  Read from Radio, it will read, then you will have a sheet to enter all your Frequencies in,  enter the tx, and rx freq, set the ctcss tone if you need one, set the power level etc... once all your repeaters are entered and any other freq's you set,  just click on Write to radio.. and thats it your memory's are programmed.  When you turn the radio on it will come on in either  Channel Mode, or Frequency mode depending on what you have set in the menu. Don't worry you have a button on the front to toggle between channel and frequency mode. Channel mode is actually memory mode,   freq mode is your VFO mode where you can punch in whatever you like.


This might seem confusing but once you have it in your hand, and look at a few Youtube videos it will become a piece of cake.  One thing I do note, is if you want to lock out a channel during a scan, you will need to do it with your USB cable and the software,  you cannot manually lock out a channel with the menu by hand. 


Good luck...