That amplifier is over 40 years old. If the high-voltage filter capacitors are original, they have failed. Seriously, if those parts are that old they should have failed ten years or more ago.
My company sells replacement power supply circuit boards for that model. The original HV boards have a design problem and will break down after the first 4 or 5 years of regular use. The one we sell is designed to last longer than that.
The low-voltage pc board underneath the small transformer also suffers wear-and-tear problems. The one we sell is an upgrade.
Typical way to locate this kind of overload issue is to start unhooking stuff. Powering it up with the tube removed, just to start.
There are two red wires coming out of the large transformer that connect to the high-voltage rectifier/filter boards. Unhooking those two wires and insulating the ends with electrical tape would be next. If it powers up this way, that's where the fault lies, most likely. And if it still trips the fuse/breaker your transformer is probably bad.
That's pretty rare in my experience.
Years ago I sold some bare pc boards to a guy who would convert the Pride to this particular tube. The socket for that tube is rare, usually more expensive than the tube that fits in it. When I asked about this, he had bought a large batch of the socket cheap. The tube would sell for around thirty bucks back then. The savings paid for the expense of replacing the socket.
Just can't remember who that was. Been at least ten years.
You really do want to hope that both transformers are okay. Nobody has those in stock any more since RF Parts ran out for good around ten years back.
73